The abnormally robust asthma pipeline with more than 100 pipeline therapies has widely promoted the research field of lung diseases

2021-12-08 08:49:21 By : Ms. Natalie Zhang

Asthma is considered to be one of the most common diseases affecting the population in the world, and it is also a life-threatening disease that affects the normal breathing of patients. Asthma has a very strong research pipeline, and there are several drug candidates in the late and mid stages of development. There are also several double and triple inhalers in the late development stage of asthma, aimed at increasing compliance rates.

Las Vegas, USA, October 20, 2021 (GLOBE NEWSWIRE) - An unusually robust asthma pipeline with more than 100 pipeline therapies has broadly promoted the research field of lung diseases

Asthma is considered to be one of the most common diseases affecting the population in the world, and it is also a life-threatening disease that affects the normal breathing of patients. Asthma has a very powerful research pipeline, with several candidates in the late and mid-stage of development. There are also several double and triple inhalers in the late development stage of asthma, aimed at increasing compliance rates.

DelveInsight's "Asthma Pipeline Insight 2021" report covers in detail the available, marketed and pipeline therapies at different stages of clinical development, major pharmaceutical companies committed to advancing the pipeline space, and the future growth potential of the asthma pipeline field.

Some important contents of the Asthma Pipeline report:

DelveInsight's asthma pipeline analysis depicts a powerful space with more than 100 active participants working to develop more than 100 pipeline treatment therapies.

Some major pharmaceutical companies working on developing potential drug candidates to improve asthma treatment options include Amgen, GlaxoSmithKline, Equillium, Viatris, Synermore Biologics, Tarus Therapeutics, Siolta Therapeutics, Chiesi Farmaceutici, Regeneron Pharmaceuticals, EURRUS Biotech, Palobiofarma SL, 4D plc, AB Science, Pearl Therapeutics, Avillion, Novartis, Celltrion, AstraZeneca, Atopix Therapeutics, Glenmark Pharmaceuticals, EMS, Biohaven Pharmaceuticals, Inc., Teva Pharmaceutical, TFF Pharmaceuticals, Inc., Shanghai Hengrui Pharmaceutical Co., Ltd., Genentech, Inc., CSL Behring, Oneness Biotech Co., Ltd., Aldeyra Therapeutics, Inc., Shanghai Biomabs Pharmaceutical Co., Ltd. Evelo Biosciences, Inc, Atridia Pty Ltd., Keymed Biosciences Co. Ltd, etc.

Basic asthma therapy, such as Tezepelumab, Depemokimab, MG 01/T 517, Masitinib, BGF MDI, NOV-14, FB704A, TEV-53275, ADX-629, FP-025, SelK2, MRx-4DP0004, AQ001S- 1703, A2BR inhibitor, PR103, KN-002, TQC2731, Zavegepant, MTPS9579A, CM326, ZL-2102, Dexpramipexole, VR588, etc. are developing clinical trials in different stages.

Tezepelumab is a research and potentially first-class human monoclonal antibody that can act on the main source of inflammation: the airway epithelium, which is the first point of contact for viruses, allergens, pollutants, and other environmental pollution. The U.S. Food and Drug Administration (FDA) has received priority review of a Biologics Licensing Application (BLA) for tezepelumab for the treatment of patients with severe asthma.

GSK'294 is an investigational drug, which may become the first biological agent to produce long-term IL-5 inhibition in SEA patients by subcutaneous injection every six months. GalaxoSmithKline was administered to the first patient in March 2021 to evaluate the effect of GSK 294 in the treatment of severe eosinophilic asthma (SEA).

The UK-based Vectura Group and Kinaset Therapeutics have reached an agreement on the development and commercialization of VR588, an inhaled pan-JAK inhibitor for the treatment of severe asthma. The drug is currently being evaluated in phase I clinical trials.

In April 2020, Leo Pharmaceuticals signed a licensing agreement with Oneness Biotech and Microbio Shanghai on the new atopic dermatitis and asthma drug candidate FB825

Aslan Pharma's product portfolio is led by ASLAN004, a new first-class antibody against IL-13 receptor, which may become the best disease for the treatment of atopic dermatitis and asthma.

In September 2021, the fixed-dose combination of salbutamol/budesonide showed promising results in phase III clinical trials.

Masitinib is another potential pipeline therapy for asthma and is being studied for the treatment of severe asthma that cannot be controlled by oral corticosteroids (OCS) and severe asthma that cannot be controlled by high-dose inhaled corticosteroids (ICS). According to reports, Masitinib has achieved positive phase III results in severe asthma that cannot be controlled by oral corticosteroids.

Request samples and learn more about the reported products @ Asthma Emerging Therapies

The Asthma Pipeline report details the pipeline assets, the comparative analysis of clinical and non-clinical asthma products, the comprehensive assessment of inactive and dormant assets, driving and inhibitory factors, and the opportunities and risks in the asthma pipeline landscape.

Asthma is a long-term disease that affects children and adults. Due to inflammation and tightening of the muscles around the small airways, the airways in the lungs become narrow. This can cause asthma symptoms: coughing, wheezing, shortness of breath and chest tightness.

The triggers for asthma vary from person to person, but may include viral infections (colds), dust, smoke, smog, weather changes, grass and tree pollen, animal fur and feathers, strong soaps and perfumes.

Learn more about this disease and its recent developments @Asthma Pipeline Assessment

Adenosine A2B receptor antagonist

Learn more about the new type of asthma pipeline therapies @ asthma pipeline analysis

The Asthma Pipeline report provides a holistic view of emerging new therapies for asthma broken down by stage, product type, molecular type, mechanism of action, and route of administration.

Adenosine A2B receptor antagonist

Scope of Asthma Pipeline Report

Main participants: Amgen, GlaxoSmithKline, Equillium, Viatris, Synermore Biologics, Tarus Therapeutics, Siolta Therapeutics, Chiesi Farmaceutici, Regeneron Pharmaceuticals, EURRUS Biotech, Palobiofarma SL, 4D Pharma plc, AB Science, Pearl Therapeutics, Novartis, Avillion Atopix Therapeutics, Glenmark Pharmaceuticals, EMS, Biohaven Pharmaceuticals, Inc., Teva Pharmaceutical, TFF Pharmaceuticals, Inc., Shanghai Hengrui Pharmaceutical Co., Ltd., Genentech, Inc., CSL Behring, Oneness Biotech Co., Ltd., Aldeyra Therapeutics , Inc., Shanghai Biomabs Pharmaceutical Co., Ltd., Suzhou Connect Biopharmaceuticals, Ltd., Kinaset Therapeutics Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Evelo Biosciences, Inc, Atridia Pty Ltd., Keymed Biosciences Co. Ltd, and others.

Main asthma pipeline therapy: Tezepelumab, Depemokimab, MG 01/T 517, Masitinib, BGF MDI, NOV-14, FB704A, TEV-53275, ADX-629, FP-025, SelK2, MRx-4DP0004, SQ0001 1703, A2BR Inhibitors, PR103, KN-002, TQC2731, Zavegepant, MTPS9579A, CM326, ZL-2102, Dexpramipexole, VR588, etc.

For more insights on emerging therapies and evaluations, please visit @Asthma Emerging Therapies

Asthma-the analytical perspective of DelveInsight

Mid-term product (Phase II)

Early product (Phase 1)

Pre-clinical and discovery stage products

Research Project: A2BR Inhibitor: Tarus Therapeutics

Asthma-market drivers and barriers

Asthma-future outlook and conclusions

For more information about current pipeline treatments for asthma, please contact @ asthma ongoing clinical trials

Track and evaluate candidates' clinical development process through actionable intelligence and comparative treatment evaluation

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